DNp69 [FBbt_20011359]

Adult descending neuron with its soma in the brain, posterior-medial to the posterior lateral protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the SMPpv2 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral inferior clamp and gorget, and presynapses in the gnathal ganglion (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the ventral median tract of ventral cervical fasciculus, and sends output to the leg neuropil and lower tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).
DNp69 DNp69

DNp69

ID: FBbt_20011359

Adult Cholinergic lineage SMPpv2 CP1

Adult descending neuron with its soma in the brain, posterior-medial to the posterior lateral protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the SMPpv2 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral inferior clamp and gorget, and presynapses in the gnathal ganglion (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the ventral median tract of ventral cervical fasciculus, and sends output to the leg neuropil and lower tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).

Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNp69 exact synonym doi_10_1101_2023_06_05_543407
DNxn094 exact synonym Stürner et al., 2025
DNp69 exact synonym doi_10_7554_eLife_97766_1
DNp69 exact synonym

List all available images of DNp69 (2 total)

Thumbnail Name Tags
TBD (MANC:11579) Adult, Cholinergic, lineage_SMPpv2_CP1
TBD (MANC:11579) Adult, Cholinergic, lineage_SMPpv2_CP1
TBD (MANC:11743) Adult, Cholinergic, lineage_SMPpv2_CP1
TBD (MANC:11743) Adult, Cholinergic, lineage_SMPpv2_CP1
TBD (MANC:11743) Adult, Cholinergic, lineage_SMPpv2_CP1

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Downstream connectivity classes for DNp69 (436 total)

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Upstream connectivity classes for DNp69 (91 total)

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