DNp57 [FBbt_20011353]

Adult descending neuron with its soma in the brain, posterior to the posterior lateral protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral superior posterior slope, and presynapses in the gnathal ganglion and the contralateral inferior and superior posterior slope (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the median tract of dorsal cervical fasciculus I and sends output to the intermediate and upper tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).
DNp57 DNp57

DNp57

ID: FBbt_20011353

Adult Cholinergic Nervous system primary neuron

Adult descending neuron with its soma in the brain, posterior to the posterior lateral protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral superior posterior slope, and presynapses in the gnathal ganglion and the contralateral inferior and superior posterior slope (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the median tract of dorsal cervical fasciculus I and sends output to the intermediate and upper tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).

Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNxn087 exact synonym Stürner et al., 2025
DNp57 exact synonym doi_10_7554_eLife_97766_1
DNp57 exact synonym doi_10_1101_2023_06_05_543407
DNp57 exact synonym

List all available images of DNp57 (2 total)

Thumbnail Name Tags
TBD (MANC:14194) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:14194) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:14337) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:14337) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:14337) Nervous_system, primary_neuron, Adult, Cholinergic

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Downstream connectivity classes for DNp57 (255 total)

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Upstream connectivity classes for DNp57 (53 total)

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