DNp53 [FBbt_20011351]

Adult descending neuron with its soma in the posterior brain, dorsal to the antler (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral and contralateral superior and inferior posterior slope, and presynapses in the gnathal ganglion and the contralateral inferior posterior slope (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the intermediate tract of dorsal cervical fasciculus - commissure of fine fibers and sends output to the intermediate and tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).
DNp53 DNp53

DNp53

ID: FBbt_20011351

Adult Cholinergic Nervous system primary neuron

Adult descending neuron with its soma in the posterior brain, dorsal to the antler (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral and contralateral superior and inferior posterior slope, and presynapses in the gnathal ganglion and the contralateral inferior posterior slope (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the intermediate tract of dorsal cervical fasciculus - commissure of fine fibers and sends output to the intermediate and tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).

Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNp53 exact synonym doi_10_7554_eLife_97766_1
DNp53 exact synonym doi_10_1101_2023_06_05_543407
DNxn084 exact synonym Stürner et al., 2025
DNp53 exact synonym

List all available images of DNp53 (2 total)

Thumbnail Name Tags
TBD (MANC:12770) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:12770) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:13034) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:13034) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:13034) Nervous_system, primary_neuron, Adult, Cholinergic

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Downstream connectivity classes for DNp53 (207 total)

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Upstream connectivity classes for DNp53 (57 total)

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