DNp48 [FBbt_20011349]

Adult descending neuron with its soma in the posterior brain, dorsal to the antler (Schlegel et al., 2024; Dorkenwald et al., 2024. It belongs to the SMPpm1 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024. In the brain, it has postsynapses in the ipsilateral superior medial protocerebrum, and presynapses in the prow, the ipsilateral and contralateral flange, the gnathal ganglion and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024. Within the VNC, it fasciculates with the median dorsal abdominal tract and sends output to the abdominal neuromere and upper tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025). (Schlegel et al., 2024, Stürner et al., 2025, Dorkenwald et al., 2024)
DNp48 DNp48

DNp48

ID: FBbt_20011349

Adult Cholinergic lineage SMPpm1 DPMm2

Adult descending neuron with its soma in the posterior brain, dorsal to the antler (Schlegel et al., 2024; Dorkenwald et al., 2024. It belongs to the SMPpm1 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024. In the brain, it has postsynapses in the ipsilateral superior medial protocerebrum, and presynapses in the prow, the ipsilateral and contralateral flange, the gnathal ganglion and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024. Within the VNC, it fasciculates with the median dorsal abdominal tract and sends output to the abdominal neuromere and upper tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025). (Schlegel et al., 2024, Stürner et al., 2025, Dorkenwald et al., 2024)

Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.

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Classification

Relationships

Alternative Names

Synonym Scope Reference
DNp48 related synonym doi_10_7554_eLife_97766_1, name_in_manc
DNp48 exact synonym doi_10_1101_2023_06_05_543407
DNxn081 exact synonym Stürner et al., 2025

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Image files aligned to TBD (MANC:13491):

Image files aligned to TBD (MANC:13203):

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References