DNp46 [FBbt_20011347]

Adult descending neuron with its soma in the posterior brain, near to the superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024. It belongs to the SMPpm1 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024. In the brain, it has postsynapses ipsilaterally in the inferior clamp and superior intermediate and medial protocerebrum, and presynapses in the gnathal ganglion and the contralateral flange (Schlegel et al., 2024; Dorkenwald et al., 2024. Within the VNC, it fasciculates with the median dorsal abdominal tract and sends output to multiple regions (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025). (Stürner et al., 2025, Dorkenwald et al., 2024, Schlegel et al., 2024)
DNp46 DNp46

DNp46

ID: FBbt_20011347

Adult Cholinergic lineage SMPpm1 DPMm2

Adult descending neuron with its soma in the posterior brain, near to the superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024. It belongs to the SMPpm1 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024. In the brain, it has postsynapses ipsilaterally in the inferior clamp and superior intermediate and medial protocerebrum, and presynapses in the gnathal ganglion and the contralateral flange (Schlegel et al., 2024; Dorkenwald et al., 2024. Within the VNC, it fasciculates with the median dorsal abdominal tract and sends output to multiple regions (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025). (Stürner et al., 2025, Dorkenwald et al., 2024, Schlegel et al., 2024)

Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.

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Classification

Relationships

Alternative Names

Synonym Scope Reference
DNp46 related synonym doi_10_7554_eLife_97766_1, name_in_manc
DNxn079 exact synonym Stürner et al., 2025
DNp46 exact synonym doi_10_1101_2023_06_05_543407

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Image files aligned to TBD (MANC:24060):

Image files aligned to TBD (MANC:23663):

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References