DNp45 [FBbt_20011346]
DNp45
ID: FBbt_20011346
Adult descending neuron with its soma in the brain, posterior to the posterior lateral protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral anterior ventrolateral protocerebrum and inferior clamp, and presynapses in the gnathal ganglion, the saddle and the ipsilateral flange (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the ventral median tract of ventral cervical fasciculus and sends output to the leg neuropil and lower tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).
Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.
Open in VFB 3D Browser →- adult cholinergic neuron
- descending neuron of the posterior brain
- primary neuron
- supraesophageal ganglion neuron
Relationships
- fasciculates with: ventral median tract of ventral cervical fasciculus
- has soma location: cell body rind of adult posterior lateral protocerebrum
- receives synaptic input in region: anterior ventrolateral protocerebrum, inferior clamp
- sends synaptic output to region: adult gnathal ganglion, adult leg neuropil, flange, lower tectulum, saddle
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| DNxn078 | exact synonym | Stürner et al., 2025 |
| DNp45 | exact synonym | doi_10_1101_2023_06_05_543407 |
| DNp45 | exact synonym | doi_10_7554_eLife_97766_1 |
| DNp45 | exact synonym |
List all available images of DNp45 (2 total)
| Thumbnail | Name | Tags |
|---|---|---|
| TBD (MANC:16842) | Nervous_system, primary_neuron, Adult, Cholinergic | |
| TBD (MANC:16842) | Nervous_system, primary_neuron, Adult, Cholinergic | |
| TBD (MANC:17575) | Nervous_system, primary_neuron, Adult, Cholinergic | |
| TBD (MANC:17575) | Nervous_system, primary_neuron, Adult, Cholinergic | |
| TBD (MANC:17575) | Nervous_system, primary_neuron, Adult, Cholinergic |
Downstream connectivity classes for DNp45 (210 total)
| Thumbnail | Name | Tags |
|---|---|---|
Upstream connectivity classes for DNp45 (75 total)
| Thumbnail | Name | Tags |
|---|---|---|
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