DNd05 [FBbt_20011339]

Adult descending neuron of the outside anterior cluster, with its soma medial to the mushroom body medial lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses ipsilaterally in the superior medial protocerebrum, gorget, vest, inferior bridge, inferior clamp and superior posterior slope, and presynapses in the gnathal ganglion (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the dorsal lateral tract of ventral cervical fasciculus and sends output to the leg neuropil (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).
DNd05 DNd05

DNd05

ID: FBbt_20011339

Adult Cholinergic Nervous system primary neuron

Adult descending neuron of the outside anterior cluster, with its soma medial to the mushroom body medial lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses ipsilaterally in the superior medial protocerebrum, gorget, vest, inferior bridge, inferior clamp and superior posterior slope, and presynapses in the gnathal ganglion (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the dorsal lateral tract of ventral cervical fasciculus and sends output to the leg neuropil (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).

Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNd05 exact synonym doi_10_1101_2023_06_05_543407
DNd05 exact synonym doi_10_7554_eLife_97766_1
DNxl026 exact synonym Stürner et al., 2025
DNd05 exact synonym

List all available images of DNd05 (2 total)

Thumbnail Name Tags
TBD (MANC:12898) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:12898) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:13238) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:13238) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:13238) Nervous_system, primary_neuron, Adult, Cholinergic

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Downstream connectivity classes for DNd05 (422 total)

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Upstream connectivity classes for DNd05 (115 total)

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