DNb08 [FBbt_20011340]

DNb08

ID: FBbt_20011340

Adult Cholinergic Nervous system primary neuron

Adult descending neuron of the anterior ventral brain (Sturner et al., 2025). It is a putative primary neuron (Schlegel et al., 2024; Dorkenwald et al., 2024. In the brain, it has presynapses in the gnathal ganglion, and the ipsilateral wedge, vest and flange, and postsynapses in the gnathal ganglion (Schlegel et al., 2024; Dorkenwald et al., 2024. Within the VNC, it fasciculates with the dorsal median tract and sends output to the leg neuropil (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 4 of these cells per organism (Takemura et al., 2024; Marin et al., 2024; Sturner et al., 2025). (Stürner et al., 2025, Schlegel et al., 2024, Dorkenwald et al., 2024)

Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.

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Classification

Relationships

capable_of_part_of: adult walking behavior
fasciculates with: adult dorsal median tract
has soma location: adult anterior brain cell body rind
receives synaptic input in region: adult gnathal ganglion, flange, vest, wedge
sends synaptic output to region: adult gnathal ganglion, adult leg neuropil

Alternative Names

Synonym	Scope	Reference
DNb08	related synonym	Berg et al., 2025, Bates et al., 2025, doi_10_7554_eLife_97766_1, name_in_banc
DNxl027	exact synonym	Stürner et al., 2025
DNb08	exact synonym	doi_10_1101_2023_06_05_543407

Downloads

Image files aligned to DNb08(VES083)_R (MaleCNS:12075):

Image files aligned to DNb08(VES082)_L (MaleCNS:12550):

Image files aligned to TBD (MANC:14966):

Image files aligned to TBD (MANC:14061):

Image files aligned to TBD (MANC:13892):

Image files aligned to BANC_626:720575941408568238:

Image files aligned to BANC_626:720575941534881368: