DNA topoisomerase type I (single strand cut, ATP-independent) activity GO_0003917
DNA topoisomerase type I (single strand cut, ATP-independent) activity
ID: GO_0003917
Class
Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity.
Open in VFB 3D Browser →Classification
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| nicking-closing enzyme activity | related synonym | 5.6.2.1 |
| untwisting enzyme activity | related synonym | 5.6.2.1 |
| swivelase activity | related synonym | 5.6.2.1 |
| omega-protein activity | related synonym | 5.6.2.1 |
| relaxing enzyme activity | related synonym | 5.6.2.1 |
| DNA topoisomerase I activity | narrow synonym | |
| topoisomerase | broad synonym | 5.6.2.1 |
| deoxyribonucleate topoisomerase | broad synonym | |
| type I topoisomerase activity | exact synonym | |
| type I DNA topoisomerase activity | exact synonym |