Dm8a [FBbt_00013774]

Glutamatergic (Gao et al., 2008; Karuppudurai et al., 2014) distal medullary amacrine neuron that branches extensively in medulla layer M6A (Fischbach and Dittrich, 1989; Takemura et al., 2013; Nern et al., 2015), spanning approximately 16 medulla columns (Karuppudurai et al., 2014), with centrifugal projections back to layer M4 (Takemura et al., 2013; Nern et al., 2015). The highest arbor density and longest distal projection are usually found in one optic column (its ‘home column’), near the center of the M6A arborization, with these columns tiling between different individual Dm8 cells, while the rest of the arbor overlaps with other Dm8 cells considerably (Gao et al., 2008; Nern et al., 2015; Kind et al., 2021). In layer M6, it is postsynaptic to several R7 photoreceptor cells and presynaptic to Tm5c (Gao et al., 2008; Takemura et al., 2013; Karuppudurai et al., 2014). The contacts with Tm5c are clustered in one column at the center of the dendritic field of Dm8 (Karuppudurai et al., 2014). It is involved in UV preference (Gao et al., 2008).
Dm8a Dm8a Dm8a Dm8a

Dm8a

ID: FBbt_00013774

Adult Glutamatergic Nervous system Visual system secondary neuron

Glutamatergic (Gao et al., 2008; Karuppudurai et al., 2014) distal medullary amacrine neuron that branches extensively in medulla layer M6A (Fischbach and Dittrich, 1989; Takemura et al., 2013; Nern et al., 2015), spanning approximately 16 medulla columns (Karuppudurai et al., 2014), with centrifugal projections back to layer M4 (Takemura et al., 2013; Nern et al., 2015). The highest arbor density and longest distal projection are usually found in one optic column (its 'home column'), near the center of the M6A arborization, with these columns tiling between different individual Dm8 cells, while the rest of the arbor overlaps with other Dm8 cells considerably (Gao et al., 2008; Nern et al., 2015; Kind et al., 2021). In layer M6, it is postsynaptic to several R7 photoreceptor cells and presynaptic to Tm5c (Gao et al., 2008; Takemura et al., 2013; Karuppudurai et al., 2014). The contacts with Tm5c are clustered in one column at the center of the dendritic field of Dm8 (Karuppudurai et al., 2014). It is involved in UV preference (Gao et al., 2008).

Connectivity inferred from EM reconstructions from a single EM section. The neurotransmitter was assessed in cells labelled with a glutamate GAL4 driver P\{GawB}vGlut[OK371] (FBti0076967) (Gao et al., 2008), RT-PCR and by immunohistochemistry (Karuppudurai et al., 2014). Connectivity with R7 was assessed by EM reconstruction of a single medulla column (Gao et al., 2008) or reconstruction of serial-section TEM (Takemura et al., 2013).

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
Dm8 exact synonym Hasegawa et al., 2011
Dm8a exact synonym Schlegel et al., 2024
Dm8a exact synonym Bates et al., 2025
Dm8a exact synonym Berg et al., 2025
Dm8a exact synonym
Dm8a exact synonym Nern et al., 2025
Dm8 exact synonym Schlegel et al., 2024
distal medullary amacrine neuron Dm8 exact synonym Hasegawa et al., 2011

List all available images of Dm8a (1315 total)

Thumbnail Name Tags
Dm8a_L (MaleCNS:164150) secondary_neuron, Nervous_system, Glutamatergic, Visual_system, Adult
Dm8a_L (MaleCNS:77983) secondary_neuron, Nervous_system, Glutamatergic, Visual_system, Adult
Dm8a_L (MaleCNS:84634) secondary_neuron, Nervous_system, Glutamatergic, Adult, Visual_system
Dm8a_R (MaleCNS:83928) secondary_neuron, Nervous_system, Glutamatergic, Adult, Visual_system
Dm8a_R (MaleCNS:91156) secondary_neuron, Nervous_system, Glutamatergic, Visual_system, Adult

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Expression patterns overlapping Dm8a (5 total)

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scRNAseq data for Dm8a (23 total)

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Transgene expression in Dm8a (4 total)

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Downstream connectivity classes for Dm8a (185 total)

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Upstream connectivity classes for Dm8a (156 total)

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