death domain binding GO_0070513
death domain binding
ID: GO_0070513
Class
Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB.
For binding to the death effector domain, consider instead the term 'death effector domain binding ; GO:0035877'.
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