TRN_VP3 [FBbt_00007576]

Adult unilateral thermosensory neuron with its sensory dendrite in an aristal sensillum and an axonal projection to antennal lobe glomerulus VP3 (Stocker et al., 1990; Alpert et al., 2020; Benton et al., 2025). It has large, elaborate sensory endings (Budelli et al., 2019). It is transiently activated by temperature decreases and transiently inhibited by temperature increases (Budelli et al., 2019). It expresses the cooling-specific Ir21a and the co-receptors Ir25a and Ir93a, with all three being required for sensitivity to cooling (Budelli et al., 2019). There are around 3-4 of these cells per hemisphere (Marin et al., 2020).
Tags:
TRN_VP3 TRN_VP3 TRN_VP3 TRN_VP3

TRN_VP3

ID: FBbt_00007576

Adult Nervous system Sensory neuron Thermosensory system

Adult unilateral thermosensory neuron with its sensory dendrite in an aristal sensillum and an axonal projection to antennal lobe glomerulus VP3 (Stocker et al., 1990; Alpert et al., 2020; Benton et al., 2025). It has large, elaborate sensory endings (Budelli et al., 2019). It is transiently activated by temperature decreases and transiently inhibited by temperature increases (Budelli et al., 2019). It expresses the cooling-specific Ir21a and the co-receptors Ir25a and Ir93a, with all three being required for sensitivity to cooling (Budelli et al., 2019). There are around 3-4 of these cells per hemisphere (Marin et al., 2020).

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
TRN_VP3a exact synonym Berg et al., 2025
cold aristal neuron exact synonym Gallio et al., 2011
TRN_VP3a exact synonym Bates et al., 2025
cooling cell exact synonym Budelli et al., 2019
TRN_VP3 exact synonym Marin et al., 2020
cold cell exact synonym Budelli et al., 2019
TRN_VP3b exact synonym Scheffer et al., 2020
ArA exact synonym Benton et al., 2025
cool cell exact synonym Liu et al., 2015
VP3RNa exact synonym Marin et al., 2020
aristal neuron (VP3) exact synonym 10368
TRN_VP3a exact synonym Scheffer et al., 2020
TRN_VP3a exact synonym Schlegel et al., 2024
cool aristal neuron exact synonym
cool thermoreceptor cells in the arista exact synonym Liu et al., 2015