long-chain (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity [GO_0016509]

Catalysis of the reaction: a long-chain (3S)-3-hydroxy fatty acyl-CoA + NAD+ = a long-chain 3-oxo-fatty acyl-CoA + H+ + NADH. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Tags:

long-chain (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity

ID: GO_0016509

Class

Catalysis of the reaction: a long-chain (3S)-3-hydroxy fatty acyl-CoA + NAD+ = a long-chain 3-oxo-fatty acyl-CoA + H+ + NADH. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.

While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).

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Classification

Alternative Names

Synonym Scope Reference
long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity related synonym 1.1.1.211
LCHAD related synonym 1.1.1.211
beta-hydroxyacyl-CoA dehydrogenase activity related synonym 1.1.1.211
long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity related synonym 1.1.1.211
long-chain-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity broad synonym

References