larval octopaminergic VPM neuron [FBbt_00047556]

Octopaminergic, bilaterally-paired neuron of the larval ventral nerve cord. Their cell bodies are found in the ventral cortex of the three subesophageal neuromeres (Selcho et al., 2014), the three thoracic neuromeres and the first abdominal neuromere, somewhat ventro-lateral to the VM fascicles (Vomel and Wegener, 2008). They form a cluster with the VUM neuron cell bodies of the same neuromere, but unlike the VUM neurons, the VPM neurons are restricted to the CNS. Most VPM neurons project anteriorly and cross the midline to arborize mainly in the contralateral neuropil (Selcho et al., 2012; Selcho et al., 2014). For neurotransmitter expression analysis, Vomel and Wegener, 2008 used Tdc2-GAL4 (tyrosine decarboxylase - implies presence of tyramine) and anti-Tbh (tyramine beta-hydroxylase - implies presence of octopamine). Selcho et al., 2012 used Tdc2-GAL4, validated with anti-Tbh, anti-p-tyramine and anti-conjugated octopamine, to visualize tyraminergic and octopaminergic neurons.

Open larval octopaminergic VPM neuron in VFB

Example Images

larval octopaminergic VPM neuron larval octopaminergic VPM neuron

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00047556",
            "symbol": "",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class",
                "Larva",
                "Nervous_system",
                "Neuron",
                "Octopaminergic"
            ],
            "short_form": "FBbt_00047556",
            "label": "larval octopaminergic VPM neuron"
        },
        "description": [
            "Octopaminergic, bilaterally-paired neuron of the larval ventral nerve cord. Their cell bodies are found in the ventral cortex of the three subesophageal neuromeres (Selcho et al., 2014), the three thoracic neuromeres and the first abdominal neuromere, somewhat ventro-lateral to the VM fascicles (Vomel and Wegener, 2008). They form a cluster with the VUM neuron cell bodies of the same neuromere, but unlike the VUM neurons, the VPM neurons are restricted to the CNS. Most VPM neurons project anteriorly and cross the midline to arborize mainly in the contralateral neuropil (Selcho et al., 2012; Selcho et al., 2014)."
        ],
        "comment": [
            "For neurotransmitter expression analysis, Vomel and Wegener, 2008 used Tdc2-GAL4 (tyrosine decarboxylase - implies presence of tyramine) and anti-Tbh (tyramine beta-hydroxylase - implies presence of octopamine). Selcho et al., 2012 used Tdc2-GAL4, validated with anti-Tbh, anti-p-tyramine and anti-conjugated octopamine, to visualize tyraminergic and octopaminergic neurons."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00058213",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class",
                "Larva",
                "Nervous_system",
                "Neuron",
                "Octopaminergic"
            ],
            "short_form": "FBbt_00058213",
            "label": "larval octopaminergic neuron"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00058214",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class",
                "Larva",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00058214",
            "label": "larval tyraminergic neuron"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002100",
                "label": "has soma location",
                "type": "has_soma_location"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00001102",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Class",
                    "Ganglion",
                    "Larva",
                    "Nervous_system"
                ],
                "short_form": "FBbt_00001102",
                "label": "larval ventral nerve cord"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [
        {
            "anatomy": {
                "symbol": "",
                "iri": "http://virtualflybrain.org/reports/VFB_00100393",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Cell",
                    "Individual",
                    "Larva",
                    "Nervous_system",
                    "Neuron",
                    "Octopaminergic",
                    "has_image",
                    "has_neuron_connectivity"
                ],
                "short_form": "VFB_00100393",
                "label": "OAN-g1 (L1EM:11525714)"
            },
            "channel_image": {
                "image": {
                    "template_channel": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFBc_00050000",
                        "types": [
                            "Entity",
                            "Individual",
                            "Template"
                        ],
                        "short_form": "VFBc_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia_c"
                    },
                    "index": [],
                    "template_anatomy": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFB_00050000",
                        "types": [
                            "Entity",
                            "Anatomy",
                            "Individual",
                            "Larva",
                            "Nervous_system",
                            "Template",
                            "has_image"
                        ],
                        "short_form": "VFB_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia"
                    },
                    "image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/0393/VFB_00050000/"
                },
                "channel": {
                    "symbol": "",
                    "iri": "http://virtualflybrain.org/reports/VFBc_00100393",
                    "types": [
                        "Entity",
                        "Individual"
                    ],
                    "short_form": "VFBc_00100393",
                    "label": "L1 CNS neuron MBE22 left_c"
                },
                "imaging_technique": {
                    "symbol": "TEM",
                    "iri": "http://purl.obolibrary.org/obo/FBbi_00000258",
                    "types": [
                        "Entity",
                        "Class"
                    ],
                    "short_form": "FBbi_00000258",
                    "label": "transmission electron microscopy (TEM)"
                }
            }
        },
        {
            "anatomy": {
                "symbol": "",
                "iri": "http://virtualflybrain.org/reports/VFB_00100404",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Cell",
                    "Individual",
                    "Larva",
                    "Nervous_system",
                    "Neuron",
                    "Octopaminergic",
                    "has_image",
                    "has_neuron_connectivity"
                ],
                "short_form": "VFB_00100404",
                "label": "OAN-g1 (L1EM:12805363)"
            },
            "channel_image": {
                "image": {
                    "template_channel": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFBc_00050000",
                        "types": [
                            "Entity",
                            "Individual",
                            "Template"
                        ],
                        "short_form": "VFBc_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia_c"
                    },
                    "index": [],
                    "template_anatomy": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFB_00050000",
                        "types": [
                            "Entity",
                            "Anatomy",
                            "Individual",
                            "Larva",
                            "Nervous_system",
                            "Template",
                            "has_image"
                        ],
                        "short_form": "VFB_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia"
                    },
                    "image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/0404/VFB_00050000/"
                },
                "channel": {
                    "symbol": "",
                    "iri": "http://virtualflybrain.org/reports/VFBc_00100404",
                    "types": [
                        "Entity",
                        "Individual"
                    ],
                    "short_form": "VFBc_00100404",
                    "label": "L1 CNS neuron MBE22 right_c"
                },
                "imaging_technique": {
                    "symbol": "TEM",
                    "iri": "http://purl.obolibrary.org/obo/FBbi_00000258",
                    "types": [
                        "Entity",
                        "Class"
                    ],
                    "short_form": "FBbi_00000258",
                    "label": "transmission electron microscopy (TEM)"
                }
            }
        }
    ],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "pmTDC2",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0210246",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0210246",
                    "label": "V\u00f6mel and Wegener, 2008, PLoS ONE 3(3): e1848"
                },
                "FlyBase": "",
                "PubMed": "18365004",
                "DOI": "10.1371/journal.pone.0001848"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ventral paired median neuron",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0219406",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0219406",
                    "label": "Selcho et al., 2012, J. Comp. Neurol. 520(16): 3764--3785"
                },
                "FlyBase": "",
                "PubMed": "22627970",
                "DOI": "10.1002/cne.23152"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "paramedial TDC2 neuron",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0210246",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0210246",
                    "label": "V\u00f6mel and Wegener, 2008, PLoS ONE 3(3): e1848"
                },
                "FlyBase": "",
                "PubMed": "18365004",
                "DOI": "10.1371/journal.pone.0001848"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ventral paired medial neuron",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0219809",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0219809",
                    "label": "Tanaka et al., 2012, J. Comp. Neurol. 520(18): 4067--4130"
                },
                "FlyBase": "",
                "PubMed": "22592945",
                "DOI": "10.1002/cne.23142"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "VPM neuron",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0225919",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0225919",
                "label": "Selcho et al., 2014, J. Comp. Neurol. 522(15): 3485--3500"
            },
            "FlyBase": "",
            "PubMed": "24752702",
            "DOI": "10.1002/cne.23616"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0219406",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0219406",
                "label": "Selcho et al., 2012, J. Comp. Neurol. 520(16): 3764--3785"
            },
            "FlyBase": "",
            "PubMed": "22627970",
            "DOI": "10.1002/cne.23152"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0210246",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0210246",
                "label": "V\u00f6mel and Wegener, 2008, PLoS ONE 3(3): e1848"
            },
            "FlyBase": "",
            "PubMed": "18365004",
            "DOI": "10.1371/journal.pone.0001848"
        }
    ]
}