larval insulin secreting cell of pars intercerebralis [FBbt_00110035]

Insulin-producing neurosecretory cell with its cell body in the larval pars intercerebralis (Ikeya et al., 2002. The same cells express Ilp2, Ilp3 and Ilp5 mRNA with different temporal profiles (Ikeya et al., 2002. An axonal branch projects to the contralateral side, looping posteriorly then anteriorly, and entering the nervus corporis cardiaci (Siegmund and Korge, 2001; Huckesfeld et al., 2021). This branch projects to the ring gland, where it has peptide release sites in the corpus cardiacum and along the aorta (Siegmund and Korge, 2001; Rulifson et al., 2002; Huckesfeld et al., 2021). Dendrites extend ventrally, close to the midline, reaching the subesophageal zone, and laterally, into the lateral protocerebrum (Siegmund and Korge, 2001; Rulifson et al., 2002; Huckesfeld et al., 2021). It receives synaptic input from hugin neurons of the protocerebrum (Schlegel et al., 2016. There are seven of these cells in each hemisphere (Cao and Brown, 2001; Rulifson et al., 2002; Ikeya et al., 2002; Park et al., 2008. (Rulifson et al., 2002, Hückesfeld et al., 2021, Siegmund and Korge, 2001, Schlegel et al., 2016, de Velasco et al., 2007, Cao and Brown, 2001, Ikeya et al., 2002, Park et al., 2008)
larval insulin secreting cell of pars intercerebralis larval insulin secreting cell of pars intercerebralis larval insulin secreting cell of pars intercerebralis larval insulin secreting cell of pars intercerebralis

larval insulin secreting cell of pars intercerebralis

ID: FBbt_00110035

Larva Nervous system Peptidergic

Insulin-producing neurosecretory cell with its cell body in the larval pars intercerebralis (Ikeya et al., 2002. The same cells express Ilp2, Ilp3 and Ilp5 mRNA with different temporal profiles (Ikeya et al., 2002. An axonal branch projects to the contralateral side, looping posteriorly then anteriorly, and entering the nervus corporis cardiaci (Siegmund and Korge, 2001; Huckesfeld et al., 2021). This branch projects to the ring gland, where it has peptide release sites in the corpus cardiacum and along the aorta (Siegmund and Korge, 2001; Rulifson et al., 2002; Huckesfeld et al., 2021). Dendrites extend ventrally, close to the midline, reaching the subesophageal zone, and laterally, into the lateral protocerebrum (Siegmund and Korge, 2001; Rulifson et al., 2002; Huckesfeld et al., 2021). It receives synaptic input from hugin neurons of the protocerebrum (Schlegel et al., 2016. There are seven of these cells in each hemisphere (Cao and Brown, 2001; Rulifson et al., 2002; Ikeya et al., 2002; Park et al., 2008. (Rulifson et al., 2002, Hückesfeld et al., 2021, Siegmund and Korge, 2001, Schlegel et al., 2016, de Velasco et al., 2007, Cao and Brown, 2001, Ikeya et al., 2002, Park et al., 2008)

Insulin-producing cells are found amongst the median neurosecretory cells, but not all mNSCs are IPCs (FBrf0212696), despite misleading phrasing in some articles (e.g. FBrf0184236). Synapsing identified in full L1 VNC EM volume - all insulin cells have connections from multiple hugin-PC cells (Schlegel et al., 2016.

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Classification

Relationships

Alternative Names

Synonym Scope Reference
IPC cell broad synonym Rulifson et al., 2002
larval corpus cardiacum and aorta innervating neurosecretory neuron of the pars intercerebralis 1 exact synonym Siegmund and Korge, 2001
PI 1-7 exact synonym Park et al., 2008
larval corpus cardiacum innervating neuron CC/A-PI 1 exact synonym Hückesfeld et al., 2021
larval mNSC DILP exact synonym doi_10_7554_eLife_102684_1
larval insulin producing cell of brain exact synonym Rulifson et al., 2002
larval dorsomedial neurosecretory cell broad synonym

Downloads

Image files aligned to IPC 4 right (L1EM:15202263):

Image files aligned to IPC 1 right (L1EM:13535380):

Image files aligned to IPC 3 left (L1EM:12634154):

Image files aligned to _IPC 2 (L1EM:10459723):

Image files aligned to IPC 4 left (L1EM:4453485):

Image files aligned to IPC 5 left (L1EM:3281684):

Image files aligned to IPC 7 left (L1EM:3046503):

Image files aligned to IPC 6 right (L1EM:2357110):

Image files aligned to _IPC 2 (L1EM:2852273):

Image files aligned to IPC 7 right (L1EM:2355126):

Graphs For

References