larval A02b neuron [FBbt_00111664]
Larval period-positive median segmental interneuron (PMSI) (Kohsaka et al., 2019) that is late-born in the NB2-1 Notch OFF primary hemilineage (Mark et al., 2021). Like other PMSIs it has a ventral soma and it extends dorsally, close to the midline, then forms a loop in the dorsal neuropil (Kohsaka et al. , 2019). This neuron has a relatively large amount of dendritic arborization around the midline, crossing into the contralateral hemineuromere (Schneider-Mizell et al., 2016; Kohsaka et al., 2019). It receives input from the proprioceptors dmd1 (dda1), ddaD and vbp, and outputs onto the ipsilateral A03a1 (eIN-4) (axo-axonic connection) and RP2 motor neuron (Schneider-Mizell et al., 2016). These neurons were identified in a EM reconstruction of a volume that includes the posterior half of abdominal segment 2 and abdominal segment 3, of a 12-24h old first instar larva. The number of connections was estimated from the publication figures. The number of input synapses was the following (number in brackets left/right; ipsi- and contralateral connections separated by comma): from dda1 (15, 15/15, 15), ddaD (10, 4/15, 15), vbp (15, 8/15, 10), A02a (8, 18/20, 18). The number of output synapses was the following: to A03a1 (15/20), A02a (5/10), A1-7 dorsal motor neuron (12/12) (Schneider-Mizell et al., 2016).
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen larval A02b neuron in VFB
Example Images
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/FBbt_00111664",
"symbol": "",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Glutamatergic",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00111664",
"label": "larval A02b neuron"
},
"description": [
"Larval period-positive median segmental interneuron (PMSI) (Kohsaka et al., 2019) that is late-born in the NB2-1 Notch OFF primary hemilineage (Mark et al., 2021). Like other PMSIs it has a ventral soma and it extends dorsally, close to the midline, then forms a loop in the dorsal neuropil (Kohsaka et al. , 2019). This neuron has a relatively large amount of dendritic arborization around the midline, crossing into the contralateral hemineuromere (Schneider-Mizell et al., 2016; Kohsaka et al., 2019). It receives input from the proprioceptors dmd1 (dda1), ddaD and vbp, and outputs onto the ipsilateral A03a1 (eIN-4) (axo-axonic connection) and RP2 motor neuron (Schneider-Mizell et al., 2016)."
],
"comment": [
"These neurons were identified in a EM reconstruction of a volume that includes the posterior half of abdominal segment 2 and abdominal segment 3, of a 12-24h old first instar larva. The number of connections was estimated from the publication figures. The number of input synapses was the following (number in brackets left/right; ipsi- and contralateral connections separated by comma): from dda1 (15, 15/15, 15), ddaD (10, 4/15, 15), vbp (15, 8/15, 10), A02a (8, 18/20, 18). The number of output synapses was the following: to A03a1 (15/20), A02a (5/10), A1-7 dorsal motor neuron (12/12) (Schneider-Mizell et al., 2016)."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00051318",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00051318",
"label": "NB2-1 Notch OFF hemilineage primary neuron"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00111047",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Glutamatergic",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00111047",
"label": "period-positive median segmental interneuron"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013009",
"label": "sends_synaptic_output_to_cell",
"type": "sends_synaptic_output_to_cell"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00001453",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Larva",
"Motor_neuron",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00001453",
"label": "RP2 motor neuron"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013008",
"label": "receives synaptic input from neuron",
"type": "receives_synaptic_input_from_neuron"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00002410",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Larva",
"Nervous_system",
"Neuron",
"Sensory_neuron"
],
"short_form": "FBbt_00002410",
"label": "abdominal dorsal multidendritic neuron ddaD"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013008",
"label": "receives synaptic input from neuron",
"type": "receives_synaptic_input_from_neuron"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00002589",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Larva",
"Nervous_system",
"Neuron",
"Sensory_neuron"
],
"short_form": "FBbt_00002589",
"label": "abdominal ventral bipolar neuron vbp"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013008",
"label": "receives synaptic input from neuron",
"type": "receives_synaptic_input_from_neuron"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00111733",
"types": [
"Entity",
"Anatomy",
"Cell",
"Cholinergic",
"Class",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00111733",
"label": "larval excitatory interneuron eIN-4"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013008",
"label": "receives synaptic input from neuron",
"type": "receives_synaptic_input_from_neuron"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00111662",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Glutamatergic",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00111662",
"label": "larval A02a neuron"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013008",
"label": "receives synaptic input from neuron",
"type": "receives_synaptic_input_from_neuron"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00111650",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Larva",
"Nervous_system",
"Neuron",
"Sensory_neuron"
],
"short_form": "FBbt_00111650",
"label": "larval abdominal dorsal multidendritic neuron dda1"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013001",
"label": "has_synaptic_IO_in",
"type": "has_synaptic_IO_in"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00001102",
"types": [
"Entity",
"Anatomy",
"Class",
"Ganglion",
"Larva",
"Nervous_system"
],
"short_form": "FBbt_00001102",
"label": "larval ventral nerve cord"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002100",
"label": "has soma location",
"type": "has_soma_location"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00111225",
"types": [
"Entity",
"Anatomy",
"Class",
"Larva",
"Nervous_system"
],
"short_form": "FBbt_00111225",
"label": "cell body rind of larval ventral nerve cord"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0000053",
"label": "bearer of",
"type": "bearer_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/PATO_0000618",
"types": [
"Entity",
"Class"
],
"short_form": "PATO_0000618",
"label": "bilateral"
}
}
],
"xrefs": [],
"anatomy_channel_image": [
{
"anatomy": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFB_00102178",
"types": [
"Entity",
"Anatomy",
"Cell",
"Glutamatergic",
"Individual",
"Larva",
"Nervous_system",
"Neuron",
"has_image",
"has_neuron_connectivity"
],
"short_form": "VFB_00102178",
"label": "A02b_a1l (L1EM:6578062)"
},
"channel_image": {
"image": {
"template_channel": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFBc_00050000",
"types": [
"Entity",
"Individual",
"Template"
],
"short_form": "VFBc_00050000",
"label": "L1 larval CNS ssTEM - Cardona/Janelia_c"
},
"index": [],
"template_anatomy": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFB_00050000",
"types": [
"Entity",
"Anatomy",
"Individual",
"Larva",
"Nervous_system",
"Template",
"has_image"
],
"short_form": "VFB_00050000",
"label": "L1 larval CNS ssTEM - Cardona/Janelia"
},
"image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/2178/VFB_00050000/"
},
"channel": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFBc_00102178",
"types": [
"Entity",
"Individual"
],
"short_form": "VFBc_00102178",
"label": "L1 CNS neuron A02b_a1l _c"
},
"imaging_technique": {
"symbol": "TEM",
"iri": "http://purl.obolibrary.org/obo/FBbi_00000258",
"types": [
"Entity",
"Class"
],
"short_form": "FBbi_00000258",
"label": "transmission electron microscopy (TEM)"
}
}
},
{
"anatomy": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFB_00102253",
"types": [
"Entity",
"Anatomy",
"Cell",
"Glutamatergic",
"Individual",
"Larva",
"Nervous_system",
"Neuron",
"has_image",
"has_neuron_connectivity"
],
"short_form": "VFB_00102253",
"label": "A02b_a1r (L1EM:15233041)"
},
"channel_image": {
"image": {
"template_channel": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFBc_00050000",
"types": [
"Entity",
"Individual",
"Template"
],
"short_form": "VFBc_00050000",
"label": "L1 larval CNS ssTEM - Cardona/Janelia_c"
},
"index": [],
"template_anatomy": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFB_00050000",
"types": [
"Entity",
"Anatomy",
"Individual",
"Larva",
"Nervous_system",
"Template",
"has_image"
],
"short_form": "VFB_00050000",
"label": "L1 larval CNS ssTEM - Cardona/Janelia"
},
"image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/2253/VFB_00050000/"
},
"channel": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFBc_00102253",
"types": [
"Entity",
"Individual"
],
"short_form": "VFBc_00102253",
"label": "L1 CNS neuron A02b_a1r _c"
},
"imaging_technique": {
"symbol": "TEM",
"iri": "http://purl.obolibrary.org/obo/FBbi_00000258",
"types": [
"Entity",
"Class"
],
"short_form": "FBbi_00000258",
"label": "transmission electron microscopy (TEM)"
}
}
}
],
"pub_syn": [
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "looper-2",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0233076",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0233076",
"label": "Zwart et al., 2016, Neuron 91(3): 615--628"
},
"FlyBase": "FBrf0233076",
"PubMed": "27427461",
"DOI": "10.1016/j.neuron.2016.06.031"
}
}
],
"def_pubs": [
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0249021",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0249021",
"label": "Mark et al., 2021, eLife 10: e67510"
},
"FlyBase": "",
"PubMed": "33973523",
"DOI": "10.7554/eLife.67510"
},
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0242656",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0242656",
"label": "Kohsaka et al., 2019, Nat. Commun. 10(1): 2654"
},
"FlyBase": "",
"PubMed": "31201326",
"DOI": "10.1038/s41467-019-10695-y"
},
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0231328",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0231328",
"label": "Schneider-Mizell et al., 2016, eLife 5: e12059"
},
"FlyBase": "",
"PubMed": "26990779",
"DOI": "10.7554/eLife.12059"
}
]
}
Feedback
Was this page helpful?
Glad to hear it! Please tell us how we can improve.
Sorry to hear that. Please tell us how we can improve.