HRN_VP1l [FBbt_00111336]

Thermosensory receptor neuron that expresses the Ionotropic receptor (Ir) 21a and innervates antennal lobe glomerulus VP1l (Marin et al., 2020; Alpert et al., 2020). It has its sensory dendrite in chamber I of the sacculus and it responds to temperature drops below 25 degrees celsius (Marin et al., 2020; Alpert et al., 2020). It develops from an Naa precursor (Benton et al., 2025). There are around 6-8 of these cells per hemisphere (Marin et al., 2020) and they are unilateral (Schlegel et al., 2021).
HRN_VP1l HRN_VP1l HRN_VP1l HRN_VP1l

HRN_VP1l

ID: FBbt_00111336

Adult Hygrosensory system Nervous system Sensory neuron Thermosensory system

Thermosensory receptor neuron that expresses the Ionotropic receptor (Ir) 21a and innervates antennal lobe glomerulus VP1l (Marin et al., 2020; Alpert et al., 2020). It has its sensory dendrite in chamber I of the sacculus and it responds to temperature drops below 25 degrees celsius (Marin et al., 2020; Alpert et al., 2020). It develops from an Naa precursor (Benton et al., 2025). There are around 6-8 of these cells per hemisphere (Marin et al., 2020) and they are unilateral (Schlegel et al., 2021).

Ir21a neuron of sacculus in original reference was speculatively assigned to sacculus chamber III and VP3 (Silbering et al., 2011). Later found to be chamber I and VP1l (Marin et al., 2020 and refs therein). Assigned to 'cold glomerulus' in Alpert et al. (2020) - FBrf0246007, but projections in AL look like VP1l projections shown in Marin et al. (2020).

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
sacculus cold cell exact synonym Alpert et al., 2020
OSN Ir21a exact synonym Silbering et al., 2011
Ir21a exact synonym Silbering et al., 2011
ORN Ir21a exact synonym
HRN_VP1l exact synonym Marin et al., 2020
ionotropic receptor neuron Ir21a exact synonym
HRN_VP1l exact synonym Berg et al., 2025
HRN_VP1l exact synonym Bates et al., 2025
VP1lRN exact synonym Marin et al., 2020
HRN_VP1l exact synonym Scheffer et al., 2020
adult olfactory receptor neuron Ir21a related synonym
HRN_VP1l exact synonym Schlegel et al., 2024

List all available images of HRN_VP1l (61 total)

Thumbnail Name Tags
HRN_VP1l_L (MaleCNS:108841198) Nervous_system, Hygrosensory_system, Sensory_neuron, Thermosensory_system, Adult, Cholinergic
HRN_VP1l_R (MaleCNS:383044585) Nervous_system, Hygrosensory_system, Sensory_neuron, Thermosensory_system, Adult, Cholinergic
HRN_VP1l_R (MaleCNS:484476) Nervous_system, Hygrosensory_system, Sensory_neuron, Thermosensory_system, Adult, Cholinergic
HRN_VP1l_R (MaleCNS:514426) Nervous_system, Hygrosensory_system, Sensory_neuron, Thermosensory_system, Adult, Cholinergic
HRN_VP1l_R (MaleCNS:588356) Nervous_system, Hygrosensory_system, Sensory_neuron, Thermosensory_system, Adult, Cholinergic

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Downstream connectivity classes for HRN_VP1l (44 total)

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Upstream connectivity classes for HRN_VP1l (19 total)

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