DNp68 [FBbt_20011358]

Adult descending neuron with its soma in the posterior brain, ventral to the mushroom body calyx (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the SMPpv2 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses ipsilaterally in the superior medial protocerebrum and inferior clamp, and presynapses in the gnathal ganglion, the ipsilateral and contralateral superior posterior slope and the saddle (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the median dorsal abdominal tract and sends output to multiple regions (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).
DNp68 DNp68

DNp68

ID: FBbt_20011358

Adult Cholinergic lineage SMPpv2 CP1

Adult descending neuron with its soma in the posterior brain, ventral to the mushroom body calyx (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the SMPpv2 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses ipsilaterally in the superior medial protocerebrum and inferior clamp, and presynapses in the gnathal ganglion, the ipsilateral and contralateral superior posterior slope and the saddle (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the median dorsal abdominal tract and sends output to multiple regions (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).

Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNp68 exact synonym doi_10_7554_eLife_97766_1
DNp68 exact synonym doi_10_1101_2023_06_05_543407
DNxn093 exact synonym Stürner et al., 2025
DNp68 exact synonym

List all available images of DNp68 (2 total)

Thumbnail Name Tags
TBD (MANC:14585) Adult, Cholinergic, lineage_SMPpv2_CP1
TBD (MANC:14585) Adult, Cholinergic, lineage_SMPpv2_CP1
TBD (MANC:15134) Adult, Cholinergic, lineage_SMPpv2_CP1
TBD (MANC:15134) Adult, Cholinergic, lineage_SMPpv2_CP1
TBD (MANC:15134) Adult, Cholinergic, lineage_SMPpv2_CP1

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Downstream connectivity classes for DNp68 (213 total)

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Upstream connectivity classes for DNp68 (89 total)

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