DNp64 [FBbt_20011357]

Adult descending neuron with its soma in the brain, posterior to the posterior lateral protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the SMPpv2 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses ipsilaterally in the anterior ventrolateral protocerebrum and inferior clamp, and presynapses in the gnathal ganglion, the ipsilateral superior medial protocerebrum, the saddle, and the contralateral flange (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the median dorsal abdominal tract and sends output to multiple regions (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).
DNp64 DNp64

DNp64

ID: FBbt_20011357

Adult Cholinergic lineage SMPpv2 CP1

Adult descending neuron with its soma in the brain, posterior to the posterior lateral protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the SMPpv2 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses ipsilaterally in the anterior ventrolateral protocerebrum and inferior clamp, and presynapses in the gnathal ganglion, the ipsilateral superior medial protocerebrum, the saddle, and the contralateral flange (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the median dorsal abdominal tract and sends output to multiple regions (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).

Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNxn091 exact synonym Stürner et al., 2025
DNp64 exact synonym doi_10_7554_eLife_97766_1
DNp64 exact synonym doi_10_1101_2023_06_05_543407
DNp64 exact synonym

List all available images of DNp64 (2 total)

Thumbnail Name Tags
TBD (MANC:17113) Adult, Cholinergic, lineage_SMPpv2_CP1
TBD (MANC:17113) Adult, Cholinergic, lineage_SMPpv2_CP1
TBD (MANC:17467) Adult, Cholinergic, lineage_SMPpv2_CP1
TBD (MANC:17467) Adult, Cholinergic, lineage_SMPpv2_CP1
TBD (MANC:17467) Adult, Cholinergic, lineage_SMPpv2_CP1

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Downstream connectivity classes for DNp64 (276 total)

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Upstream connectivity classes for DNp64 (46 total)

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