DNp59 [FBbt_20011332]

Adult descending neuron with its soma in the posterior brain, dorsal to the antler (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral inferior clamp, superior medial protocerebrum, superior posterior slope and inferior bridge, and presynapses in the gnathal ganglion, the ipsilateral cantle and the saddle (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the median dorsal abdominal tract and sends output to the lower tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is GABA (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).
DNp59 DNp59

DNp59

ID: FBbt_20011332

Adult GABAergic Nervous system primary neuron

Adult descending neuron with its soma in the posterior brain, dorsal to the antler (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral inferior clamp, superior medial protocerebrum, superior posterior slope and inferior bridge, and presynapses in the gnathal ganglion, the ipsilateral cantle and the saddle (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the median dorsal abdominal tract and sends output to the lower tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is GABA (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).

Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNp59 exact synonym doi_10_7554_eLife_97766_1
DNp59 exact synonym doi_10_1101_2023_06_05_543407
DNlt008 exact synonym Stürner et al., 2025
DNp59 exact synonym

List all available images of DNp59 (2 total)

Thumbnail Name Tags
TBD (MANC:12698) Nervous_system, primary_neuron, GABAergic, Adult
TBD (MANC:12698) Nervous_system, primary_neuron, GABAergic, Adult
TBD (MANC:12783) Nervous_system, primary_neuron, Adult, GABAergic
TBD (MANC:12783) Nervous_system, primary_neuron, Adult, GABAergic
TBD (MANC:12783) Nervous_system, primary_neuron, Adult, GABAergic

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Downstream connectivity classes for DNp59 (259 total)

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Upstream connectivity classes for DNp59 (87 total)

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