DNp49 [FBbt_20007549]

Adult descending neuron with its soma in the brain, posterior-ventral to the mushroom body calyx (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the PSp3 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral and contralateral superior posterior slope, and the ipsilateral inferior clamp and inferior bridge, and presynapses in the gnathal ganglion (Schlegel et al., 2024; Dorkenwald et al., 2024). In the VNC, it follows the dorsal lateral tract of ventral cervical fasciculus (Sturner et al., 2025). Its predicted neurotransmitter is glutamate (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).
DNp49 DNp49 DNp49 DNp49

DNp49

ID: FBbt_20007549

Adult Glutamatergic lineage PSp3 DPMl1

Adult descending neuron with its soma in the brain, posterior-ventral to the mushroom body calyx (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the PSp3 lineage (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral and contralateral superior posterior slope, and the ipsilateral inferior clamp and inferior bridge, and presynapses in the gnathal ganglion (Schlegel et al., 2024; Dorkenwald et al., 2024). In the VNC, it follows the dorsal lateral tract of ventral cervical fasciculus (Sturner et al., 2025). Its predicted neurotransmitter is glutamate (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).

Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are the fewest regions that collectively contain at least 80 percent of all pre- or post-synapses of these neurons in FlyWire.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNp49 exact synonym Bates et al., 2025
DNp49 exact synonym doi_10_7554_eLife_97766_1
DNp49 exact synonym Schlegel et al., 2024
DNp49 exact synonym Berg et al., 2025
DNxn082 exact synonym Stürner et al., 2025
DNp49 exact synonym

List all available images of DNp49 (12 total)

Thumbnail Name Tags
DNp49_L (MaleCNS:11204) lineage_PSp3_DPMl1, Glutamatergic, Adult
DNp49_L (MaleCNS:11204) lineage_PSp3_DPMl1, Glutamatergic, Adult
DNp49_R (MaleCNS:11298) lineage_PSp3_DPMl1, Glutamatergic, Adult
DNp49_R (MaleCNS:11298) lineage_PSp3_DPMl1, Glutamatergic, Adult
TBD (MANC:11268) lineage_PSp3_DPMl1, Glutamatergic, Adult

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Downstream connectivity classes for DNp49 (401 total)

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Upstream connectivity classes for DNp49 (290 total)

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