DNp47 [FBbt_20011348]

Adult descending neuron with its soma in the brain, posterior to the posterior lateral protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral superior posterior slope and inferior clamp, and presynapses in the ipsilateral superior posterior slope, the gnathal ganglion, the saddle and the ipsilateral inferior clamp (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the dorsal median tract and sends output to the leg neuropil and lower tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).
DNp47 DNp47

DNp47

ID: FBbt_20011348

Adult Cholinergic Nervous system primary neuron

Adult descending neuron with its soma in the brain, posterior to the posterior lateral protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral superior posterior slope and inferior clamp, and presynapses in the ipsilateral superior posterior slope, the gnathal ganglion, the saddle and the ipsilateral inferior clamp (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the dorsal median tract and sends output to the leg neuropil and lower tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025).

Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNp47 exact synonym doi_10_7554_eLife_97766_1
DNp47 exact synonym doi_10_1101_2023_06_05_543407
DNxn080 exact synonym Stürner et al., 2025
DNp47 exact synonym

List all available images of DNp47 (2 total)

Thumbnail Name Tags
TBD (MANC:13226) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:13226) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:13764) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:13764) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:13764) Nervous_system, primary_neuron, Adult, Cholinergic

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Downstream connectivity classes for DNp47 (276 total)

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Upstream connectivity classes for DNp47 (36 total)

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