DNge053 [FBbt_20007365]
DNge053
ID: FBbt_20007365
Adult descending neuron of the DNge053 group, with its soma in the brain, ventral to the antennal mechanosensory and motor center (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). It has pre- and post-synapses in the gnathal ganglion and saddle and additionally receives input in the ipsilateral and contralateral vest (Schlegel et al., 2024; Dorkenwald et al., 2024). It enters the VNC via the cervical connective, then fasciculates with the dorsal median tract, sending output to multiple regions (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Cell type from Schlegel et al. (2024), based on FlyWire v783 (FAFB) data (Dorkenwald et al., 2024; Schlegel et al., 2024) and identified at light level by Sapkal et al. (2024). Soma location based on the closest annotated neuropil region. Neurotransmitter predictions are from Eckstein et al. (2024). Other annotations are based on annotations in FlyWire and are available in the supplemental material of Schlegel et al. (2024). Full name for BDN1 from codex (2025-03-04).
Open in VFB 3D Browser →Relationships
- bearer of: bilateral
- capable_of_part_of: adult walking behavior
- fasciculates with: adult dorsal median tract
- receives synaptic input in region: adult gnathal ganglion, saddle, vest
- sends synaptic output to region: adult gnathal ganglion, saddle
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| DNxn164 | exact synonym | Sapkal et al., 2024 |
| DNge053 | exact synonym | Schlegel et al., 2024 |
| DNge053 | exact synonym | Bates et al., 2025 |
| adult BDN1 neuron | exact synonym | Sapkal et al., 2024 |
| DNxn164 | exact synonym | doi_10_7554_eLife_97766_1 |
| adult major bolt protocerebral neuron output descending neuron 1 | exact synonym | |
| DNge053 | exact synonym | Berg et al., 2025 |
| DNxn164 | exact synonym |
List all available images of DNge053 (8 total)
| Thumbnail | Name | Tags |
|---|---|---|
| DNge053_L (MaleCNS:10844) | Nervous_system, primary_neuron, Adult, Cholinergic | |
| DNge053_L (MaleCNS:10844) | Nervous_system, primary_neuron, Adult, Cholinergic | |
| DNge053_R (MaleCNS:11965) | Nervous_system, primary_neuron, Adult, Cholinergic | |
| DNge053_R (MaleCNS:11965) | Nervous_system, primary_neuron, Adult, Cholinergic | |
| TBD (MANC:13291) | Nervous_system, primary_neuron, Adult, Cholinergic |
Downstream connectivity classes for DNge053 (428 total)
| Thumbnail | Name | Tags |
|---|---|---|
Upstream connectivity classes for DNge053 (345 total)
| Thumbnail | Name | Tags |
|---|---|---|
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