DNge053 [FBbt_20007365]

Adult descending neuron of the DNge053 group, with its soma in the brain, ventral to the antennal mechanosensory and motor center (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). It has pre- and post-synapses in the gnathal ganglion and saddle and additionally receives input in the ipsilateral and contralateral vest (Schlegel et al., 2024; Dorkenwald et al., 2024). It enters the VNC via the cervical connective, then fasciculates with the dorsal median tract, sending output to multiple regions (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
DNge053 DNge053 DNge053 DNge053

DNge053

ID: FBbt_20007365

Adult Cholinergic Nervous system primary neuron

Adult descending neuron of the DNge053 group, with its soma in the brain, ventral to the antennal mechanosensory and motor center (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). It has pre- and post-synapses in the gnathal ganglion and saddle and additionally receives input in the ipsilateral and contralateral vest (Schlegel et al., 2024; Dorkenwald et al., 2024). It enters the VNC via the cervical connective, then fasciculates with the dorsal median tract, sending output to multiple regions (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).

Cell type from Schlegel et al. (2024), based on FlyWire v783 (FAFB) data (Dorkenwald et al., 2024; Schlegel et al., 2024) and identified at light level by Sapkal et al. (2024). Soma location based on the closest annotated neuropil region. Neurotransmitter predictions are from Eckstein et al. (2024). Other annotations are based on annotations in FlyWire and are available in the supplemental material of Schlegel et al. (2024). Full name for BDN1 from codex (2025-03-04).

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNxn164 exact synonym Sapkal et al., 2024
DNge053 exact synonym Schlegel et al., 2024
DNge053 exact synonym Bates et al., 2025
adult BDN1 neuron exact synonym Sapkal et al., 2024
DNxn164 exact synonym doi_10_7554_eLife_97766_1
adult major bolt protocerebral neuron output descending neuron 1 exact synonym
DNge053 exact synonym Berg et al., 2025
DNxn164 exact synonym

List all available images of DNge053 (8 total)

Thumbnail Name Tags
DNge053_L (MaleCNS:10844) Nervous_system, primary_neuron, Adult, Cholinergic
DNge053_L (MaleCNS:10844) Nervous_system, primary_neuron, Adult, Cholinergic
DNge053_R (MaleCNS:11965) Nervous_system, primary_neuron, Adult, Cholinergic
DNge053_R (MaleCNS:11965) Nervous_system, primary_neuron, Adult, Cholinergic
TBD (MANC:13291) Nervous_system, primary_neuron, Adult, Cholinergic

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Downstream connectivity classes for DNge053 (428 total)

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Upstream connectivity classes for DNge053 (345 total)

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