DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity [GO_0072587]

Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.

Open DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity in VFB

VFB Term Json

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        "description": [
            "Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
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            "short_form": "GO_0008047",
            "label": "enzyme activator activity"
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    "relationships": [
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                "label": "positively regulates",
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