DNA topoisomerase type I (single strand cut, ATP-independent) activity [GO_0003917]
Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle. Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen DNA topoisomerase type I (single strand cut, ATP-independent) activity in VFB
VFB Term Json
{
"term": {
"core": {
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"types": [
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],
"short_form": "GO_0003917",
"label": "DNA topoisomerase type I (single strand cut, ATP-independent) activity"
},
"description": [
"Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle."
],
"comment": [
"Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
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"iri": "http://purl.obolibrary.org/obo/GO_0003916",
"types": [
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"short_form": "GO_0003916",
"label": "DNA topoisomerase activity"
}
],
"relationships": [],
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"pub_syn": [
{
"synonym": {
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{
"synonym": {
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},
{
"synonym": {
"scope": "has_broad_synonym",
"label": "deoxyribonucleate topoisomerase",
"type": ""
},
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"FlyBase": "",
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},
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "DNA topoisomerase I activity",
"type": ""
},
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}
}
],
"def_pubs": []
}
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