C2 FBbt_00003743
C2
ID: FBbt_00003743
Adult centrifugal neuron with arborizations in the medulla layers M1, M5/M6, M8 and M10 and more restricted arborizations in the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021. In the medulla, it makes reciprocal connections to lamina monopolar neuron L1, and is presynaptic to L2 and L5, as well as medullary intrinsic neuron Mi1 (Takemura et al., 2013. It is GABAergic (Fei et al., 2010. There is usually one of these cells per optic column (Nern et al., 2025. (Meinertzhagen and O'Neil, 1991, Takemura et al., 2013, Fischbach and Dittrich, 1989, Kind et al., 2021, Takemura et al., 2008, Fei et al., 2010, Rivera-Alba et al., 2011)
Pre- versus postsynaptic innervation in the proximal medulla was inferred by scoring of terminal morphology from figures in Fischbach and Dittrich, 1989 as assessed by FlyBrain Neuron DB. Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013.
Open in VFB 3D Browser →Classification
Relationships
- receives synaptic input from neuron: lamina monopolar neuron L1
- receives synaptic input in region: lamina, medulla layer M1, medulla layer M10, medulla layer M5, medulla layer M8
- sends synaptic output to cell: lamina monopolar neuron L1, lamina monopolar neuron L2, lamina monopolar neuron L5, medulla intrinsic neuron Mi1
- sends synaptic output to region: lamina, medulla layer M1
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| C2 | related synonym | Berg et al., 2025, Bates et al., 2025, name_in_male-cns, Nern et al., 2025, Schlegel et al., 2024 |
| C2 | exact synonym | Özel et al., 2021 |
Cross References
- C2 on FlyBrain NeuronDB (10079)
Downloads
Image files aligned to C2_R (MaleCNS:98537):
Image files aligned to C2_R (MaleCNS:88581):
Image files aligned to C2_R (MaleCNS:63213):
Image files aligned to C2:
Image files aligned to C2:
Image files aligned to C2:
Image files aligned to C2_R (JRC_OpticLobe:100256):
Image files aligned to C2_R (JRC_OpticLobe:91572):
Image files aligned to C2_R (JRC_OpticLobe:83976):
Image files aligned to C2_R (MaleCNS:88581):
List all available images of C2 (7295 total)
| Thumbnail | Name | Tags |
|---|---|---|
 | C2_L (MaleCNS:123993) | Nervous_system, Adult, GABAergic, Visual_system |
 | C2_L (MaleCNS:132130) | Nervous_system, Adult, GABAergic, Visual_system |
 | C2_L (MaleCNS:157692) | Nervous_system, GABAergic, Adult, Visual_system |
 | C2_R (MaleCNS:101438) | Nervous_system, Visual_system, GABAergic, Adult |
 | C2_R (MaleCNS:101831) | Nervous_system, Adult, GABAergic, Visual_system |
View all 7295 results in VFB →
Splits targeting C2 (3 total)
scRNAseq data for C2 (24 total)
| Thumbnail | Name | Tags |
|---|---|---|
| scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_C2_neurons | Adult, Cluster, Nervous_system | |
| scRNAseq_2018_Davie_FULL_seq_clustering_C2_neurons | Adult, Cluster, Nervous_system | |
| scRNAseq_2021_Ozel_ADM1_seq_clustering_C2_neurons | Adult, Cluster, Nervous_system | |
| scRNAseq_2022_FCA_FEMALE_FULL_seq_clustering_C2_centrifugal_neurons | Adult, Cluster, Nervous_system | |
| scRNAseq_2022_FCA_FEMALE_HEAD_seq_clustering_C2_centrifugal_neurons | Adult, Cluster, Nervous_system |
Downstream connectivity classes for C2 (272 total)
| Thumbnail | Name | Tags |
|---|---|---|
Upstream connectivity classes for C2 (333 total)
| Thumbnail | Name | Tags |
|---|---|---|