aminoacyl-tRNA ligase activity [GO_0004812]
Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP. Note that the bond resulting from this reaction is a carboxylic acid ester bond, linking the alpha carboxyl group of the amino acid to either the 2’ or 3’ hydroxyl of the 3’- terminal adenyl residue of the tRNA.
Note
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VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0004812",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0004812",
"label": "aminoacyl-tRNA ligase activity"
},
"description": [
"Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP."
],
"comment": [
"Note that the bond resulting from this reaction is a carboxylic acid ester bond, linking the alpha carboxyl group of the amino acid to either the 2' or 3' hydroxyl of the 3'- terminal adenyl residue of the tRNA."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0016875",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0016875",
"label": "ligase activity, forming carbon-oxygen bonds"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0140101",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0140101",
"label": "catalytic activity, acting on a tRNA"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_broad_synonym",
"label": "ligase activity, forming aminoacyl-tRNA and related compounds",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_related_synonym",
"label": "aminoacyl-tRNA synthetase auxiliary protein activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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