adult olfactory receptor neuron Ir64a [FBbt_00110019]
Bilateral olfactory receptor neuron that expresses the ionotropic glutamate receptor (Ir) 64a (FBgn0035604) and the co-receptor Ir8a (FBgn0052704). Its axon branches, with one branch innervating an ipsilateral antennal lobe glomerulus and the other fasciculating with the antennal commissure and innervating the corresponding contralateral lobe glomerulus. Two subtypes are identified: one innervates the antennal lobe DC4 glomerulus and the other innervates the medial compartment of DP1 glomerulus. Its dendrite transduces signals from the grooved sensillum of chamber III of the sacculus (Shanbhag et al., 1995). This neuron was indirectly shown to be olfactory by recording calcium changes in the antennal lobe during an odorant-response assay using wildtype flies and mutants in which ORN Ir64a were silenced (Ai et al., 2010).
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VFB Term Json
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