Activated type I receptor phosphorylates R-Smad1/5/8 directly [GO_0004675]
Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
Note
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VFB Term Json
{
"term": {
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"symbol": "",
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"short_form": "GO_0004675",
"label": "Activated type I receptor phosphorylates R-Smad1/5/8 directly"
},
"description": [
"Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
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"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0019199",
"types": [
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],
"short_form": "GO_0019199",
"label": "JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0004674",
"types": [
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],
"short_form": "GO_0004674",
"label": "Activation of NLK"
}
],
"relationships": [
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"label": "is part of",
"type": "part_of"
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"object": {
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"iri": "http://purl.obolibrary.org/obo/GO_0007178",
"types": [
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"short_form": "GO_0007178",
"label": "transmembrane receptor protein serine/threonine kinase signaling pathway"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_related_synonym",
"label": "receptor protein serine/threonine kinase activity",
"type": ""
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"pub": {
"core": {
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"iri": "http://flybase.org/reports/Unattributed",
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"short_form": "Unattributed",
"label": ""
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"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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